What is
Bonlecule?

The name Bonlecule is originated from the words bone and molecule. OSSFILA believes Bonlecule will be a building block of artificial bones and other tissues which can communicate well inside the body.

Mission impossible Nanomaterials

Mission impossible Nanomaterials

Through our state of the art nanomaterial technology, nano-hydroxapatite crystals are successfully grown on nano-co-polymers. The sub-100nm nano-hydroxyapatite crystals have shown the same electron diffraction pattern as human hydroxyapatite crystals extracted from trabeculae in selected area electron diffraction (SAED) in TEM. Sub-500nm nano-co-polymers allow seamless distribution with the polymer matrix which resemble the FDM filament.  

 

Mission impossible Nanomaterials

Upscale Clean Production

In OSSFILA, all nano-particles and crystals are synthesized in industrial scale under close supervision of our engineers and scientists. The incorporation of nano-particles in the polymer matrix during filament extrusion is engineered to produce excellent dispersion and to perfect the printing experience in any commercial 3D printer. All the manufacturing processes are done in ISO 14644-1 Class 10,000 cleanroom and is under strict quality control governed by ISO 13485. 

Super Functional Biomaterial

Super Functional Biomaterial

Bonlecule is a groundbreaking functional biomaterial. It has superior biological and mechanical properties compared to any biomaterial building block on the market. Conventional biomaterials improve on bioactivity through filler materials or coatings. In FDM filament, filler materials will contribute to the brittleness and filament may break at the printer nozzle. Coating is also not possible for making uniform continuum required for 3D printing. The solution to this limitation is to utilize bioactive nano-particles with engineered dispersion process during production. 

Bonlecule Hydroxyapatite
TEM SAED

 

“Hydroxyapatite grown in our reactor has the same characteristics TEM SAED peaks of human natural hydroxyapatite.”

Bonlecule
Mineralization &
Cell Proliferation

MC3T3-E1

“Osteoblastic cell line MC3T3-E1 showed more than 228% of cell proliferation in 3 days. Significant mineralization could be seen in 28 days.”